FEATURES

FAMILY

krueppel C2H2-type zinc-finger protein family

DESCRIPTION

Also known as ZNF91_HUMAN, ZNF91. Transcription factor specifically required to repress SINE-VNTR-Alu (SVA) retrotransposons: recognizes and binds SVA sequences and represses their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). May also bind the promoter of the FCGR2B gene, leading to repress its expression; however, additional evidence is required to confirm this result in vivo (PubMed:11470777).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ZNF91

Zinc finger protein 91

ZNF91

Molecular Synopsis