FEATURES

FAMILY

DESCRIPTION

Also known as VMAT2_HUMAN, SLC18A2, SVMT, VMAT2. Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles (PubMed:23363473). Requisite for vesicular amine storage prior to secretion via exocytosis. Interacts with SLC6A3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC18A2

Synaptic vesicular amine transporter

SLC18A2

Molecular Synopsis