FEATURES

FAMILY

DESCRIPTION

Also known as TERT_YEAST, EST2. Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalytic subunit of the telomerase holoenzyme complex composed minimally of EST2 and the telomerase RNA template component.

EXTERNAL LINKS

uniprot
enzyme classification

EST2

Telomerase reverse transcriptase

EST2

Structural Ligandability

Domains Chains

Distribution