FEATURES

FAMILY

eukaryotic NMN adenylyltransferase family

DESCRIPTION

Also known as NMA1_YEAST, NMA1. Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate to form deamido-NAD(+) (NaAD). Key enzyme in both de novo and salvage pathways for NAD(+) biosynthesis. Predominantly acts in the salvage pathways via NMN. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification

NMA1

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

NMA1

Structural Ligandability

Domains Chains

Distribution