rep (Replicase polyprotein 1ab)
FEATURES
Loading...
Loading...
ORGANISM
Lactate dehydrogenase elevating virus (strain C)
FAMILY
DESCRIPTION
Also known as RPOA_LDVC, rep. The replicase polyprotein 1ab is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products., The Nsp1 chain is essential for viral subgenomic mRNA synthesis., The 3C-like serine proteinase chain is responsible for the majority of cleavages as it cleaves the C-terminus of the polyprotein., The helicase chain, which contains a zinc finger structure, displays RNA and DNA duplex-unwinding activities with 5' to 3' polarity.
Also known as RPOA_LDVC, rep. The replicase polyprotein 1ab is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products., The Nsp1 chain is essenti
rep logo

rep

Replicase polyprotein 1ab

Molecular Synopsis