FEATURES

FAMILY

eukaryotic ribosomal protein eL24 family

DESCRIPTION

Also known as RLP24_YEAST, RLP24. Involved in the biogenesis of the 60S ribosomal subunit (PubMed:12808088, PubMed:23185031). Ensures the docking of NOG1 to pre-60S ribosomal particles (PubMed:12808088). Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles (PubMed:23185031). Associated with nucleolar and cytoplasmic pre-60S particles (PubMed:12808088). At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24 (PubMed:12808088, PubMed:23185031). Interacts (via C-terminus) with AFG2 (hexameric form); the interaction is direct, recruits AFG2 to pre-60S ribosomal particles and promotes AFG2 ATPase activity and RLP24 release from pre-60S ribosomal particles (PubMed:23185031). Interacts with NOG1; the interaction is direct (PubMed:12808088).

EXTERNAL LINKS

RLP24

Mutations

Mutation(s) distribution

Mutations table