FEATURES

FAMILY

DESCRIPTION

Also known as THII_SHEFN, thiI. Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.

EXTERNAL LINKS

uniprot
enzyme classification

thiI

tRNA sulfurtransferase

thiI

Molecular Synopsis