FEATURES

DESCRIPTION

Also known as RGS1_HUMAN, RGS1, 1R20, BL34, IER1. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541). Interacts with GNAI1 and GNAQ.

Also known as RGS1_HUMAN, RGS1, 1R20, BL34, IER1. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leuk ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RGS1

Regulator of G-protein signaling 1

RGS1

Molecular Synopsis