FEATURES

FAMILY

DESCRIPTION

Also known as MCA1_YEAST, MCA1, YCA1. Cysteine protease that cleaves specifically after arginine or lysine residues (PubMed:22761449). Mediates cell death (apoptosis) triggered by oxygen stress, salt stress or chronological aging. Regulated cell death can prevent a release of toxic cellular components, thus avoiding necrotic collapse of the colony, and can also provide nutrients for healthy cells. Therefore, regulated cell death in yeast colonies can be as important for their development as are apoptosis and related processes that occur within metazoa. Promotes the removal of insoluble protein aggregates during normal growth. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

MCA1

Metacaspase-1

MCA1

Molecular Synopsis