FEATURES

FAMILY

DESCRIPTION

Also known as WDR6_YEAST, RTT10, ERE2, TRM734. Involved in regulation of Ty1 transposition. Plays also a role in the regulation of the retromer complex and is required for the recycling from endosomes of plasma membrane proteins like CAN1 and MUP1. Required together with TRM7 for the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)). Interacts with RRT2. Interacts with TRM7; for 2'-O-methylation of position 34 in substrate tRNAs.

EXTERNAL LINKS

uniprot
enzyme classification

RTT10

Regulator of Ty1 transposition protein 10

Mutations

Mutation(s) distribution

Mutations table

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