FEATURES

FAMILY

DESCRIPTION

Also known as SCF_CHICK, KITLG, SCF. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). Homodimer, non-covalently linked.

EXTERNAL LINKS

uniprot
enzyme classification

KITLG

Kit ligand

KITLG

Structural Ligandability

Domains Chains

Distribution