KITLG (Kit ligand)
FEATURES
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ORGANISM
Gallus gallus
FAMILY
DESCRIPTION
Also known as SCF_CHICK, KITLG, SCF. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). Homodimer, non-covalently linked.
Also known as SCF_CHICK, KITLG, SCF. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathwa
KITLG logo

KITLG

Kit ligand

Molecular Synopsis