FEATURES

FAMILY

DESCRIPTION

Also known as APS1_SCHPO, aps1. Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate). Also catalyzes the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

aps1

Diphosphoinositol polyphosphate phosphohydrolase aps1

aps1

Structural Ligandability

Domains Chains

Distribution