FEATURES

FAMILY

DESCRIPTION

Also known as MUG_SHIF8, mug. Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells. Binds DNA as a monomer.

Also known as MUG_SHIF8, mug. Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It ...

EXTERNAL LINKS

uniprot
enzyme classification

mug

G/U mismatch-specific DNA glycosylase

mug

Structural Ligandability

Domains Chains

Distribution