TOF1 (Topoisomerase 1-associated factor 1)
FEATURES
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ORGANISM
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
FAMILY
DESCRIPTION
Also known as TOF1_PHANO, TOF1. Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
Also known as TOF1_PHANO, TOF1. Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpo
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TOF1

Topoisomerase 1-associated factor 1

Molecular Synopsis