FEATURES

FAMILY

DESCRIPTION

Also known as DBP_HUMAN, DBP. This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. Binds DNA as a homodimer or a heterodimer. Can form a heterodimer with TEF.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DBP

D site-binding protein

DBP

Molecular Synopsis