FEATURES

FAMILY

DESCRIPTION

Also known as TBP_EMENI, tbpA, tbp. General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Belongs to the TFIID complex together with the TBP-associated factors (TAFs). Binds DNA as monomer.

EXTERNAL LINKS

uniprot
enzyme classification

tbpA

TATA-box-binding protein

tbpA

Structural Ligandability

Domains Chains

Distribution