FEATURES

DESCRIPTION

Also known as NBR1_HUMAN, NBR1, 1A13B, KIAA0049, M17S2. Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets. Homooligomer and heterooligomer. Interacts with TRIM55 (By similarity). Interacts with SQSTM1, titin/TTN, RNF29, USP8, SQSTM1, MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2. Binds to ubiquitin and ubiquitinated proteins.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NBR1

Next to BRCA1 gene 1 protein

Mutations

Mutation(s) distribution

Mutations table

Search Mutation