FEATURES

FAMILY

DESCRIPTION

Also known as GNMT_HUMAN, GNMT. Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GNMT

Glycine N-methyltransferase

Mutations

Mutation(s) distribution

Mutations table

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