FEATURES

FAMILY

DESCRIPTION

Also known as GRM3_HUMAN, GRM3, GPRC1C, MGLUR3. G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. Interacts with TAMALIN.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GRM3

Metabotropic glutamate receptor 3

GRM3

Molecular Synopsis