FEATURES

DESCRIPTION

Also known as PUM3_HUMAN, PUM3, cPERP-C, KIAA0020, PUF-A, XTP5. Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity). Interacts with PARP1 (via catalytic domain).

Also known as PUM3_HUMAN, PUM3, cPERP-C, KIAA0020, PUF-A, XTP5. Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:2126 ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PUM3

Pumilio homolog 3

PUM3

Molecular Synopsis