FEATURES

FAMILY

DESCRIPTION

Also known as RYR3_HUMAN, RYR3, HBRR. Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling. Homotetramer. Heterotetramer with RYR2. Interacts with CALM (By similarity). Interacts with FKBP1A. Interacts with SELENON (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RYR3

Ryanodine receptor 3

RYR3

Molecular Synopsis