FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as ACHA6_HUMAN, CHRNA6. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR seems to be composed of two different types of subunits: alpha and non-alpha (beta). Interacts with LYPD6 (PubMed:27344019).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHRNA6

Neuronal acetylcholine receptor subunit alpha-6

CHRNA6

Molecular Synopsis