FEATURES

FAMILY

DESCRIPTION

Also known as DPYL2_HUMAN, DPYSL2, CRMP2, ULIP2. Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.

Also known as DPYL2_HUMAN, DPYSL2, CRMP2, ULIP2. Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Neces ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DPYSL2

Mutations

Mutation(s) distribution

Mutations table