FEATURES

FAMILY

DESCRIPTION

Also known as CALRL_HUMAN, CALCRL, CGRPR. Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:22102369, PubMed:30115739). Heterodimer of CALCRL and RAMP3 (By similarity). Heterodimer of CALCRL and RAMP1 or CALCRL and RAMP2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CALCRL

Calcitonin gene-related peptide type 1 receptor

CALCRL

Molecular Synopsis