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FEATURES

FAMILY

peptidase S1 family

DESCRIPTION

Also known as PRSS8_HUMAN, PRSS8. Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). Heterodimer of two chains, light and heavy, held by a disulfide bond.

Also known as PRSS8_HUMAN, PRSS8. Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cl ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PRSS8

Prostasin

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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