FEATURES

FAMILY

DESCRIPTION

Also known as SECA2_CLOD6, secA2. Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

EXTERNAL LINKS

uniprot
enzyme classification

secA2

Mutations

Mutation(s) distribution

Mutations table