FEATURES

FAMILY

DESCRIPTION

Also known as IMA3_CAEEL, ima-3. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs. Necessary for correct nucleoporin localization within the germline., Essential gene for embryonic and larval development. Required for oogenic development, ima-1 and ima-2 cannot functionally compensate for loss of ima-3. Forms a complex with an importin beta subunit.

EXTERNAL LINKS

uniprot
enzyme classification

ima-3

Importin subunit alpha-3

ima-3

Molecular Synopsis