FEATURES

FAMILY

DESCRIPTION

Also known as ECSCR_HUMAN, ECSCR, ECSM2. Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. Interacts with FLNA. Interacts with the 20S proteasome subunit PSMA7.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ECSCR

Endothelial cell-specific chemotaxis regulator

ECSCR

Molecular Synopsis