recU (Holliday junction resolvase RecU)

FEATURES

FAMILY

DESCRIPTION

Also known as RECU_STRPC, recU. Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

recU

Holliday junction resolvase RecU

LIGANDABILITY MUTATIONS

recU

Molecular Synopsis