FEATURES

FAMILY

FAD-binding oxidoreductase/transferase type 4 family

DESCRIPTION

Also known as D2HDH_BOVIN, D2HGDH. Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate (By similarity). Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC) (By similarity). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

D2HGDH

D-2-hydroxyglutarate dehydrogenase, mitochondrial

D2HGDH

Structural Ligandability

Domains Chains

Distribution