FEATURES

FAMILY

DESCRIPTION

Also known as EIF3A_CHAGB, TIF32. RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

EXTERNAL LINKS

uniprot
enzyme classification

TIF32

Eukaryotic translation initiation factor 3 subunit A

TIF32

Structural Ligandability

Domains Chains

Distribution