No data available

FEATURES

DESCRIPTION

Also known as COMD6_BOVIN, COMMD6. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Inhibits TNF-induced NFKB1 activation. Homodimer. Interacts (via COMM domain) with COMMD1 (via COMM domain). Does not interact with NFKBIB. Interacts with RELA, RELB, NFKB1/p105. Does not interact with NFKBIB. Interacts with CCDC22, CCDC93, SCNN1B, CUL4A.

Also known as COMD6_BOVIN, COMMD6. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Inhibits TNF-induced NFKB1 activation. Homodimer. Interacts (via COMM domain) with COMMD1 ...

EXTERNAL LINKS

uniprot
enzyme classification

COMMD6

COMM domain-containing protein 6

Structural Ligandability

Domains Chains

Distribution

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