FEATURES

FAMILY

DESCRIPTION

Also known as KI26B_HUMAN, KIF26B. Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity). Interacts with MYH10.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KIF26B

Kinesin-like protein KIF26B

KIF26B

Molecular Synopsis