FEATURES

FAMILY

Orn/Lys/Arg decarboxylase class-II family

DESCRIPTION

Also known as BTRK_BACCI, btrK. Pyridoxal phosphate-dependent decarboxylase that catalyzes 1 step in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Able to decarboxylate L-ornithine, L-arginine, L-lysine, but not L-glutamate or any D-amino acids. Has low activity with substrates not bound to an acyl-carrier protein. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

btrK

L-glutamyl-[BtrI acyl-carrier protein] decarboxylase

btrK

Molecular Synopsis