FEATURES

FAMILY

DESCRIPTION

Also known as KIF4B_HUMAN, KIF4B. Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis (By similarity). Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis (By similarity). May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KIF4B

Chromosome-associated kinesin KIF4B

KIF4B

Molecular Synopsis