FEATURES

FAMILY

class-V pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as AGT_AEDAE, AGT. Catalyzes the pyridoxal 5'-phosphate-dependent transamination of alanine with glyoxylate as an amino group acceptor (PubMed:16681462). Can also catalyze, although with much less efficiency, the transamination of serine, and histidine with glyoxylate and the and transamination of glycine with pyruvate as an amino group acceptor (PubMed:16681462). Does not catalyze the transamination of both 3-hydroxykynurenine and L-kynurenine (PubMed:16681462). May play a role in the detoxification of glyoxylate, a toxic plant metabolite from the pupae and adult diet (Probable). Homodimer.

EXTERNAL LINKS

AGT

Mutations

Mutation(s) distribution

Mutations table