FEATURES

FAMILY

shaker potassium channel beta subunit family

DESCRIPTION

Also known as GPR_ECOLI, gpr, mgrA, yghZ. Catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP, which may be formed by non-enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification

gpr

L-glyceraldehyde 3-phosphate reductase

Mutations

Mutation(s) distribution

Mutations table

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