FEATURES

FAMILY

DESCRIPTION

Also known as TCDA_ECOLI, tcdA, csdL, ygdL. Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine. TcdA is also part of a sulfur transfer pathway; is able to accept sulfur from CsdA directly in vitro, but CsdE might act as the sulfur donor in vivo. Interacts with CsdE.

EXTERNAL LINKS

uniprot
enzyme classification

tcdA

tRNA threonylcarbamoyladenosine dehydratase

tcdA

Molecular Synopsis