FEATURES

FAMILY

DESCRIPTION

Also known as NADA_ASPFU, nadA. Conidial surface nicotinamide adenine dinucleotide glycohydrolase that cleave NAD(+) and NADP(+) but not their reduced counterparts, NADH and NADPH (PubMed:33712585). Lacks both ADP-ribosyl cyclase and base exchange activity and does not mediate synthesis of calcium messengers cADPR or NAADP (PubMed:33712585). Plays a role in pathogenicity by depleting the host's NAD(+) pool (PubMed:33712585). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

nadA

Conidial surface nicotinamide adenine dinucleotide glycohydrolase nadA

nadA

Molecular Synopsis