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FAMILY

non-heme iron-dependent dioxygenase family

DESCRIPTION

Also known as HPPE_STRWE, hppE, fom4. Non-heme-dependent dioxygenase that catalyzes the oxidative epoxidation of (S)-2-hydroxypropylphosphonate into (1R, 2S)-epoxypropylphosphonate, the final step in the biosynthesis of fosfomycin antibiotic. Homotetramer.

Also known as HPPE_STRWE, hppE, fom4. Non-heme-dependent dioxygenase that catalyzes the oxidative epoxidation of (S)-2-hydroxypropylphosphonate into (1R, 2S)-epoxypropylphosphonate, the final step ...

EXTERNAL LINKS

uniprot
enzyme classification

hppE

(S)-2-hydroxypropylphosphonic acid epoxidase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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