Retreg1 (Reticulophagy regulator 1)
FEATURES
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ORGANISM
Rattus norvegicus
FAMILY
DESCRIPTION
Also known as RETR1_RAT, Retreg1, Fam134b. Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Required for long-term survival of nociceptive and autonomic ganglion neurons. Interacts with ATG8 family modifier proteins MAP1LC3A, MAP1LC3B, GABARAP, GABARAPL1 and GABARAPL2.
Also known as RETR1_RAT, Retreg1, Fam134b. Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Requi
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Retreg1

Reticulophagy regulator 1

Molecular Synopsis