FEATURES

FAMILY

DESCRIPTION

Also known as SPX_STAAC, spx. Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator. Interacts with the C-terminal domain of the alpha subunit of the RNAP.

EXTERNAL LINKS

uniprot
enzyme classification

spx

Global transcriptional regulator Spx

spx

Structural Ligandability

Domains Chains

Distribution