FEATURES

FAMILY

DESCRIPTION

Also known as SPA3G_MOUSE, Serpina3g, Spi2A. Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.

Also known as SPA3G_MOUSE, Serpina3g, Spi2A. Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against ...

EXTERNAL LINKS

uniprot
enzyme classification

Serpina3g

Serine protease inhibitor A3G

Serpina3g

Structural Ligandability

Domains Chains

Distribution