FEATURES

FAMILY

DESCRIPTION

Also known as KA157_ANDAM, KA157. Blocker of A-type voltage-gated potassium channels of cerebellar granular cells. May also inhibit Kv4/KCND when coexpressed with DPP6 or DPP10. The occlusion of the outer entry of the K(+) conducting pore is partially reversible and affects both open and closed channels. It shares the same target in rat brain than BmTX3 (AC Q8I0L5) and AmmTX3 (AC P60208).

EXTERNAL LINKS

uniprot
enzyme classification

KA157

Potassium channel toxin alpha-KTx 15.7

KA157

Structural Ligandability

Domains Chains

Distribution