FEATURES

FAMILY

DESCRIPTION

Also known as TPM3_BOVIN, TPM3. Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Homodimer. Heterodimer of an alpha (TPM1, TPM3 or TPM4) and a beta (TPM2) chain. Interacts with TMOD1.

EXTERNAL LINKS

uniprot
enzyme classification

TPM3

Tropomyosin alpha-3 chain

TPM3

Structural Ligandability

Domains Chains

Distribution