FEATURES

FAMILY

DESCRIPTION

Also known as CLIC2_RAT, Clic2. Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx (By similarity). Monomer. Interacts with TRAPPC2 and RYR2 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Clic2

Chloride intracellular channel protein 2

Clic2

Molecular Synopsis