FEATURES

DESCRIPTION

Also known as ITLN1_XENLA, itln1. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:26755729). Binds to microbial glycans that contain a terminal acyclic 1, 2-diol moiety, including beta-linked D-galactofuranose (beta-Galf) and D-phosphoglycerol-modified glycans (PubMed:26755729). Binds to S.pneumoniae serotypes with glycans that contain beta-linked D-galactofuranose (beta-Galf) and with D-phosphoglycerol-modified glycans (PubMed:26755729). Can bind a variety of monosaccharides (in vitro) (PubMed:15537792). Probably plays a role in the defense system against microorganisms (Probable). Homotrimer; disulfide-linked (PubMed:26755729). Homohexamer; disulfide-linked (PubMed:15537792, PubMed:26755729). Forms primarily homotrimers in solution, but can also form homohexamers (PubMed:26755729).

EXTERNAL LINKS

itln1

Intelectin-1

itln1

Molecular Synopsis