FEATURES

FAMILY

pyrroline-5-carboxylate reductase family

DESCRIPTION

Also known as P5CR3_RAT, Pycr3, Pycrl. Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. Homodecamer; composed of 5 homodimers.

EXTERNAL LINKS

uniprot
enzyme classification

Pycr3

Pyrroline-5-carboxylate reductase 3

Pycr3

Structural Ligandability

Domains Chains

Distribution