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FEATURES

FAMILY

isocitrate and isopropylmalate dehydrogenases family

DESCRIPTION

Also known as LEU3_THET8, leuB. Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Homodimer.

Also known as LEU3_THET8, leuB. Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 o ...

EXTERNAL LINKS

uniprot
enzyme classification

leuB

3-isopropylmalate dehydrogenase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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